Nhau - Kushandiswa kweZinc Oxid Yakajairika Mukudzivirira Manyoka eNguruve Dzidiki

Ini.

Zinc oxide, inozivikanwa se zinc white, i amphotericzinc oxideiyo isinganyungudike mumvura asi inonyungudika muasidhi uye alkali yakasimba. Fomura yayo yemakemikari iZnO, huremu hwemamorekuru i81.37, nhamba yeCAS i1314-13-2, nzvimbo yekunyungudika i1975℃ (kuora), nzvimbo yekufashaira i2360℃, uye hainyungudike mumvura. Inoshandiswa zvakanyanya munzvimbo dzinopfuura makumi maviri dzakadai semapurasitiki, zvigadzirwa zvesilicate, rabha yekugadzira, mafuta ekuzora, pendi nependi, mafuta ekuzora, zvinonamira, chikafu, mabhatiri, zvinodzora moto,nezvimwewo.

Mufananidzo 1Zinc oxidemuenzaniso

III. Matambudziko ekuita manyoka munguruve dzakarumurwa uye kukosha kwechirwere ichizinc oxide

Kurumura mwana inyaya inoshungurudza zvikuru muhupenyu hwenguruve. Matambudziko akadai sekushaya simba kwemudumbu, kusakwana kwekubudisa ma enzymes ekugaya chikafu, uye kusaenzana kwemiti zvinowanzo konzera manyoka mushure mekurumura mwana (PWD), izvo zvinokanganisa zvakanyanya kukura kwenguruve uye mabhenefiti ekubereka. Sezvo nguruve dzichiri kurwara, dzinofanira kutarisirwa zvakanyanya.zinc oxideZvakaonekwa kuti zvine mhedzisiro yakakura pakurwisa manyoka muma1980, zvave "chiyero chegoridhe" cheindasitiri yezvemhuka pasi rose kubata nevanorwara. Zvidzidzo zvakaratidza kuti kuwedzera 2500-3000 mg/kgzinc oxideinogona kuderedza huwandu hwemanyoka ne40%-60%, ukuwo ichiwedzera kuwedzera uremu zuva nezuva ne10%-15%. Kukosha kwayo kukuru kuri mukudzikamisa nharaunda yemudumbu nekukurumidza kuburikidza nenzira dzakasiyana-siyana, zvichipa dziviriro yakakosha yekuchinja kwenguruve.

Matambudziko emanyoka munguruve dzakarumurwa uye kukosha kwe zinc oxide mukurapa

IV.Maitiro ekuita kwezinc oxidekurwisa manyoka

1)Kusimbisa chidziviriro chemuviri chemudumbu

Zinc oxideZvinokurudzira kuwanda kwemasero epithelial emudumbu, zvinowedzera zvakanyanya chiyero chehurefu hwemudumbu kusvika pakadzika kwecrypt, zvinovandudza nzvimbo yepamusoro yekunyudzwa kwezvinovaka muviri, uye panguva imwe chete zvinosimudzira kuratidzwa kwemapuroteni akamanikana (Occludin, ZO-1), zvinoderedza kupinda kwemudumbu mudumbu, uye zvinodzivirira kupinda kwezvirwere. Zvinodzivirira mashandiro emudumbu mudumbu, zvinovandudza kugona kwenguruve kubata mabhakitiriya, uye zvinoderedza manyoka.

Mufananidzo 2Mhedzisiro yedosi dzakasiyana dzezinc oxidepamusoro pemaumbirwo emukati menguruve

Mufananidzo 3 Mhedzisiro yemhando dzakasiyana dzezinc oxide pamapuroteni emudumbu ane tight junction munguruve diki

Mufananidzo 3Mhedzisiro yedosi dzakasiyana dzezinc oxidepamapuroteni emudumbu akasungwa munguruve

2)Kudzora kuenzana kwehutachiona hwemudumbu

Zinc oxideinogadzira hydrogen peroxide free radicals mudumbu, inova chinhu chakakosha mukushanda kweantibacterial kwezinc oxide. Mushonga wakakwirazinc oxideInodzivisa zvakananga kuwanda kwemabhakitiriya anokonzera zvirwere akadai seEscherichia coli neSalmonella nekuburitsa reactive oxygen species (ROS), ukuwo ichikurudzira kupinda kwemabhakitiriya anobatsira akadai seLactobacillus.

Mufananidzo 4Mhedzisiro yekudyazinc oxidepazvipembenene zve cecal munguruve diki

3) Zinc yakawanda inokurudzira kukura kwenguruve

Kushungurudzika kwekurumura mwana kunokonzera kudzikira kwekugaya chikafu ne30%, uye kugayiwa kwezvinovaka muviri munguruve dzakarumurwa kunowedzera kuderera kana dziri mumamiriro ekuita manyoka. Zvidzidzo zvakaratidza kutiizvokuwedzera madosi akawanda ezinc oxidekudya kunogona kuwedzera huwandu hwe zinc muropa, kuwedzera kudzora kuburitswa kwemapeptides emudumbu uye mahormone enzarauyekukurudzira vana venguruve kuti vadye. Panguva imwe, kuwedzera kwe zinc muropakanizvinobudirira kukurudzira kugadzirwa uye kuvhurwa kwema enzymes ekugaya chikafu, kuvandudza kugayiwa kwezvinovaka muviriuyekuwedzera huremu hwenguruve dzevana zuva nezuva.

Mufananidzo 5Mhedzisiro ye zinc oxide pakukura kwenguruve dzakarumurwa

IV. Hurongwa hweSainzi uye Nzira dzeKudzivirira

1. Chipimo chakarurama uye kutenderera kwekushandiswa

Kunyangwe zvichitaurwa kuti zinc yakawanda (1600-2500 mg/kg)zinc oxide) chikafu chinogona kushandiswa chete mu""mavhiki maviri ekutanga mushure mekubvisa mwana"", mapurazi mazhinji enguruve anowedzera kushandiswa kwechikafu chine zinc yakawanda kwemavhiki maviri kusvika masere. Panguva ino, mamwe mapurazi enguruve achaona""migumisiro ine zinc yakawanda"", izvo zvinowanzoonekwa sebvudzi gobvu uye refu uye ganda risina kujeka.

2. Sarudzazinc oxidenekugadzikana kwakanyanya kuvandudza mhedzisiro yechigadzirwa

Kuwanikwa kwehupenyu hwemuvirizinc oxideinogadzirwa nemaitiro ekunyorova yakakwira zvakanyanya kupfuura iyo yezinc oxidezvinogadzirwa nenzira yakananga. Saka, pakusarudzazinc oxidezvigadzirwa, maitiro ekugadzira kwayo anofanirawo kufungwa nezvawo.

5. Mafambiro Eindasitiri uye Maonero Etekinoroji Akafanana

Kunyangwe EU yakaganhurira huwandu hwezinc inowedzerwa kusvika pa150 mg/kg, tsika dzemuno dzinoratidza kuti kutsiva zinc yakawanda zvachose kuchiri kutarisana nematambudziko ehunyanzvi. Zvimwe zvinoshandiswa pari zvino zvakaita se nano nano zvinowedzerwa.zinc oxide(300 mg/kg) uye basic zinc chloride (1200 mg/kg) zvinogona kuderedza chiyero, asi mutengo wazvo wakakwira, kugadzikana kwemaitiro hakuna kukwana, uye kuchengetedzeka kwenguva refu kuchiri kufanira kusimbiswa. Nokudaro,zvakajairikazinc oxideichiri sarudzo yakanakisisa yemapurazi madiki nepakati kuti mutengo nemhedzisiro zvienzane.