Kushandiswa kweHydroxy Methionine Copper 1

Zvishandiso zveChigadzirwa

1) Makuro enyama

Kana MMHAC (hydroxy methionine chelates yemhangura, zinc, uye manganese) zvakawedzerwa mukudya kwehuku dzenyama, mhedzisiro yakaratidza kuti—zvichienzaniswa nemaminerari echinyakare asina kugadzirwa—kuiswa kweMMHAC kwakawedzera zvakanyanya huremu hwemuviri uye huremu hwetsandanyama dzechidya, kugaya mhangura kwakawedzera, uye hakuna kukanganisa hutano hwegumbo kana mapfupa.

Tafura 1. Huremu hwekugadzirisa nyama (g/shiri) uye matanda ezamu nechipfuva chena chemhando yebroilers dzakapihwa inorganic ne methionine hydroxyl analogue chelated zinc, copper, uye manganese dietary treatment sat 42 day.

Chinhu	ITM	M10	T125	M30	SEM	P-Kukosha
Zamu	684	716	719	713	14.86	0.415
Chidya	397	413	412	425	7.29	0.078
Chirauro cheDrumstick	320	335	332	340	4.68	0.058
Chidya nedrumstick	717 a	748 ab	745 ab	765 b	11.32	0.050
Pedhi yemafuta	32.3	33.1	33.4	35.5	1.59	0.546
Chiropa	68.0	67.4	66.0	71.1	2.41	0.528
Mwoyo	18.8	18.6	19.2	19.2	0.68	0.898
Itsvo	9.49	10.2	10.6	10.6	0.51	0.413

Cherechedza: ITM: Zvicherwa zvisina kusimba 110 ppm Zn seZnSO4 16 ppm Cu seCuSO4 uye120 ppm Mn seMnO paRoss 308 mazano ezvekudya;

M10: Huwandu hwe40 ppm Zn 10 ppm Cu uye 40 ppm Mn se chelate;

T125: Zvicherwa zvisingasanganisike 110 ppm Zn seZnSO4 uye 120 ppm Mn seMnO paRoss 308 nhungamiro dzine 125 ppm Cu se tribasic copper chloride (TBCC);

M30 = 40 ppm Zn, 30 ppm Cu, uye 40 ppm Mn se chelate. Makoshero ari mumutsara mumwe chete ane ma superscript akasiyana akasiyana anosiyana zvakanyanya (P < 0.05).

2) Nguruve

Chidzidzo chakaongorora migumisiro yekutsiva zvishoma zvicherwa zvisingawanikwe ne mineral methionine hydroxy analogue chelates (MMHAC) mukudya kwenguruve nenguruve dzadzo. Zvakawanikwa zvakaratidza kuti kuwedzerwa kweMMHAC kwakaderedza kudzikira kwehuremu hwemuviri munguruve dzinoyamwisa, kwakasimudzira kuwedzera kwehuremu hwemuviri wenguruve pazuva rechi18, kwakavandudza zvakanyanya huwandu hwehistone acetylation yemhasuru dzemapfupa pakuzvarwa, uye kwakaderedza kuratidzwa kwemajini akawanda ane chekuita nekuzvimba uye kukura kwetsandanyama. Kazhinji, MMHAC yakavandudza hutano hwemudumbu nekukura kwetsandanyama munguruve kuburikidza ne epigenetic uye developmental regulation, zvichiwedzera kugona kwavo kukura.

Tafura 2 Migumisiro yekuwedzera ye mineral methionine hydroxy analogue chelate mukudya kwemhuka yenguruve pakuratidza key mRNA ine chekuita nekuzvimba kwejejunal munguruve inoyamwa.

Chinhu	ITM	CTM	SEM	P- kukosha
d 1 yekuyamwisa x 10^-5
IL-8	1344	1018	178	0.193
MUC2	5380	5511	984	0.925
NF-κB (p50)	701	693	93	0.944
NF-κB (p105)	1991	1646	211	0.274
TGF-b1	Kubva muna 1991	1600	370	0.500
TNF-α	11	7	2	0.174
d 18 yekuyamwisa x 10^-5
IL-8	1134	787	220	0.262
MUC2	5773	3871	722	0.077

Cherechedza: Interleukin-8 (IL-8), mucin-2 (MUC2), nuclear factor-κB (NF-κB), transforming growth factor-1 (TGF-1), uye tumor necrosis factor-α (TNF-α)

ITM = manyuko echinyakare ezvicherwa zvidiki (0.2% yehuwandu hwezvicherwa mukudya)

CTM = 50:50 mineral methionine hydroxy analogue chelate uye inorganic minerals (0.2% inclusion level mukudya)

3)Zvipfuyo zvinodya nyama

Mumombe dzinoyamwisa, kutsiva hafu ye copper sulfate nehydroxy methionine mhanguraZvakawedzera zvakanyanya huwandu hwemhangura muropa, zvakavandudza kugayiwa kwefiber ye detergent isina kusimba (NDF) uye acid detergent fiber (ADF), uye zvakawedzera goho remukaka uye kugadzirwa kwemukaka wakagadziriswa mafuta ne4%. Zvakawanikwa izvi zvinoratidza kuti kutsiva copper sulfate ne (HMTBA)₂-Cu mukudya kwemombe dzemukaka inzira inoshanda zvakanyanya yekudya.

Tafura 3 Mhedzisiro yemethionine hydroxy Cu [(HMTBA)2-Cu] pamukaka wemombe

Chinhu	S	SM	M	SEM	P-kukosha
DMI, kg/d	19.2	20.3	19.8	0.35	0.23
Kukura kwemukaka, kg/zuva	28.8	33.8	31.3	1.06	0.08
Mafuta, %	3.81	3.74	3.75	0.06	0.81
Mapuroteni, %	3.34	3.28	3.28	0.04	0.19
Lactose, %	4.48	4.35	4.43	0.05	0.08
SNF, %	8.63	8.84	8.63	0.05	0.33
Goho remafuta, kg/d	1.04	1.22	1.10	0.04	0.09
Goho remapuroteni, kg/zuva	0.92	0.92	0.90	0.03	0.72
Goho reLactose, kg/zuva	1.23	1.23	1.21	0.04	0.45
Urea N, mg/dL	18.39	17.70	18.83	0.45	0.19
4% FCM, kg/zuva	26.1	30.1	27.5	0.91	0.06

Kurapa: S = Cu sulfate chete: 12 mg yeCu inopihwa neCuSO4 pa kilogiramu ye concentrate; SM = Cu sulfate uye (HMTBA)2-Cu: 6 mg yeCu inopihwa neCuSO4, uye imwe 6 mg yeCu inopihwa ne (HMTBA)2-Cu pa kilogiramu ye concentrate; M = (HMTBA)2-Cu chete: 12 mg yeCu inopihwa ne (HMTBA)2-Cu pa kilogiramu ye concentrate.